Often asked: In eukaryotes, how can a single gene code for several different proteins?

How can a single gene code for several different proteins?

Gene splicing is a post-transcriptional modification in which a single gene can code for multiple proteins. During a typical gene splicing event, the pre-mRNA transcribed from one gene can lead to different mature mRNA molecules that generate multiple functional proteins.

How can one eukaryotic gene lead to one transcript but multiple different proteins?

How do they lead to the production of multiple proteins from a single gene? Alternative processing of pre-mRNA can take the form of either alternative splicing of pre-mRNA introns or the alternative cleavage of 3′ cleavage sites in a pre-mRNA molecule containing two or more cleavage sites for polyadenylation.

How many different proteins can be made from a single gene?

McKusick, of the Johns Hopkins University School of Medicine, says, “It seems to be a matter of five or six proteins, on average, from one gene.” McKusick, who is a co-author of the Science paper, suggests that people who now claim that the number of human genes is much higher, may be looking at and counting separate

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Does a single gene code for a single protein?

The genome of an organism is inscribed in DNA, or in some viruses RNA. The portion of the genome that codes for a protein or an RNA is referred to as a gene. Those genes that code for proteins are composed of tri-nucleotide units called codons, each coding for a single amino acid.

Can mRNA codes for more than one protein?

mRNAs carry the genetic information that is translated by ribosomes. Thus, the expression of two or more proteins translated from the same mRNA may offer a mechanism to ensure the co-expression of proteins which have functional interactions.

What is silent gene?

Silent genes are generally found in more compact regions of chromatin, termed heterochromatin, while active genes are in regions of euchromatic chromatin which is less compact and more permissible for proteins to bind.

What is a major disadvantage to a bacterial cell of having an operon?

What is a major disadvantage to a bacterial cell of having an operon? If there is a mutation in a regulatory region, none of the proteins will be synthesized. RNA polymerase. They give the cell tight control over transcription.

What is alternative splicing how does it lead to the production of multiple proteins from a single gene?

Alternative splicing is the process of selecting different combinations of splice sites within a messenger RNA precursor (pre-mRNA) to produce variably spliced mRNAs. These multiple mRNAs can encode proteins that vary in their sequence and activity, and yet arise from a single gene.

What is the primary transcript of eukaryotic genes?

A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation.

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How many human proteins are known?

In humans, up to ten different proteins can be traced to a single gene. Proteome: It is now estimated that the human body contains between 80,000 and 400,000 proteins. However, they aren’t all produced by all the body’s cells at any given time. Cells have different proteomes depending on their cell type.

Do all genes code for proteins?

Arrayed along the DNA strand are the genes, specific regions whose sequences carry the genetic code for making specific proteins. The genes of bacteria are tightly packed together; virtually all the DNA encodes proteins. It is estimated that only about five percent of human DNA encodes protein.

Can more than one protein be produced from the same gene?

Scientists have long known that it’s possible for one gene to produce slightly different forms of the same protein by skipping or including certain sequences from the messenger RNA. Human genes typically contain several “exons,” or DNA sequences that code for amino acids, the building blocks of proteins.

What proteins do genes code for?

A gene is the section of DNA required to produce one protein. Genes are typically hundreds or thousands of base pairs in length because they code for proteins made of hundreds or thousands of amino acids. Most genes contain the information needed to make functional molecules called proteins.

How do you read genetic codes?

The genetic code consists of the sequence of bases in DNA or RNA. Groups of three bases form codons, and each codon stands for one amino acid (or start or stop). The codons are read in sequence following the start codon until a stop codon is reached. The genetic code is universal, unambiguous, and redundant.

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What is the code for a specific amino acid?

three nucleotides—called a triplet or codon—codes for one particular amino acid in the protein. The nucleotide sequence in the DNA is first transcribed into a molecule of messenger RNA (ribonucleic acid).

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